He is the recipient of numerous international prizes, including the Queen Elisabeth Competition in Brussels and a 2009 Borletti-Buitoni Trust Fellowship. In September 2009, BBC named Francesco one of its „New Generation Artists". Francesco Piemontesi has made guest appearances at the BBC Proms, Lucerne Festival, Edinburgh Festival, Schleswig-Holstein, Mecklenburg-Vorpommern, City of London Festival, Martha Argerich Project, Cheltenham, Ruhr, Rheingau, Schubertiade Hohenems, Bad Kissingen, Roque d'Anthéron Festivals.
He has played as soloist with the London Philharmonic, BBC Symphony Orchestra, Symphonieorchester des Bayerischen Rundfunks, City of Birmingham Symphony Orchestra, Rundfunk-Sinfonieorchester Berlin, Israel Philharmonic Orchestra, Orchestre Philharmonique de Monte Carlo, Orchestre de la Suisse Romande, Bournemouth Symphony, Singapore Symphony, Maggio Musicale Fiorentino, Scottish Chamber Orchestra, Sinfonia Varsovia, the Zurich and Vienna Chamber Orchestras, the Orchestre de Chambre de Lausanne collaborating with conductors as Zubin Mehta, Marek Janowski, Jiri Belohlavek, Sakari Oramo, Lawrence Foster, Mikhail Pletnev, Christoph Poppen, Vassily Sinaisky, Vassily Petrenko, Thierry Fischer and Jean-Claude Casadesus.
Highlights of following seasons include performances with the Philharmonia Orchestra, NHK Symphony Orchestra, Deutsches Symphonieorchester Berlin, Sao Paolo Symphony under Sir Roger Norrington, Marek Janowski, Heinrich Schiff and Stanislaw Skowaczewski. Piemontesi will give recitals at Wigmore Hall in London, Concertgebouw in Amsterdam, Salle Gaveau in Paris, Aix-en-Provence Festival, Miami Piano Festival, Meunhin Festival Gstaad.
Francesco nurtures a special artistic interest in chamber music. He has played with Yuri Bashmet, Renaud und Gautier Capuçon, Bruno Giuranna, Daniel Müller-Schott, Emmanuel Pahud, Heinrich Schiff, Jörg Widmann and the Ebène quartet.
He has recorded for EMI Classics. In 2012 he signed an exclusive contract with Naive Classique. The next CD will include the Piano Concerti by Schumann and Dvorak together with the BBC Symphony and Jiri Belohlavek and will be published in Spring 2013.